APO-SYS Consortium

 

Apoptosis Systems Biology Applied to Cancer and AIDS

 

An integrated approach of experimental biology, data mining, mathematical modeling, biostatistics, system engineering and molecular medicine

Publications

2007

  1. Babaie Y, Herwig R, Greber B, Brink TC, Wruck W, Groth D, Lehrach H, Burdon T, Adjaye J. Analysis of Oct4- dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells. 2007: 25, 500-10.

  1. Buttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, Sigrist C, Wissing S, Kollroser M, Frohlich KU, Sigrist S, Madeo F. Endonuclease g regulates budding yeast life and death. Molecular Cell. 2007: 25, 233-46.

  1. Cohen, IR, and Harel, D. Explaining a Complex Living System: Dynamics, Multi-scaling and Emergence. J. Royal Society Interface, 2007: 4, 175-82.

  1. Efroni, S., Harel, D. and Cohen, IR. Emergent Dynamics of Thymocyte Development and Lineage Determination. PLOS Computational Biology, 2007: 3, 127-36.

  1. Høyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Elling F, Rizzuto R, Mathiasen IS, Jäättelä M. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-ß and Bcl-2. Mol Cell 2007: 25, 193-205.

  1. Huber HJ, Rehm M, Plucht M, Prehn JH. APOPTO-CELL - A simulation tool and interactive database for analyzing cellular susceptibility to apoptosis. Bioinformatics.  2007 Mar 1; 23(5):648-50.

  2. LaFerla-Brühl, K., Westhoff, M.A., Kasperczyk, H., Zwacka, R.M., Debatin, K. M, Fulda, S. NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. Oncogene, 2007: 26, 571-82.

  1. Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, Castedo M, Mignot G, Metivier D,Larochette D, van Edert P, Ciccosanti F, Piacentini F, Zitvogel L, Kroemer G. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med. 2007: 13, 54-61.

  1. Opel D, Poremba, C., Simon T, Fulda S. Activation of the PI3K/Akt pathway predicts poor outcome in neuroblastoma. Cancer Res. 2007: 67, 735-45

  1. Park, H. H., Logette, E., Raunser, S., Cuenin, S., Walz, T., Tschopp, J., and Wu, H. Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex. Cell 2007: 128, 533-46.

  1. Rapaport F, Zinovyev A, Dutreix M, Barillot E, and Vert J.P. Classification of microarray data using gene networks. BMC Bioinformatics. 2007: 8, 35.

  1. Vande Walle, L, Van Damme, P, Lamkanfi, M, Saelens, X, Vandekerckhove, J, Gevaert, K, Vandenbeele, P. Proteome-wide identification of HtrA2/Omi substrates. J Proteome Res, 2007: 6(3):1006-1015.





 





Publications

2010

2009

2008

2007