APO-SYS Consortium
Apoptosis Systems Biology Applied to Cancer and AIDS
An integrated approach of experimental biology, data mining, mathematical modeling, biostatistics, system engineering and molecular medicine
APO-SYS Public
Deliverables
DL 4: Training for mastering
the interface for pathway map description integration:
DL4-apo-sys
DL5: Initial launch of APO-SYS Web server and
internal web resources for data sharing and communication:
DL5-apo-sys
DL6: Data
management workshop and workshop report on consortium requirements for
sharing of high quality annotation of molecular entities:
DL6-apo-sys
DL7: Data
management workshop and workshop report on consortium requirements for
sharing of high-throughput data, definition of standards to be used for
all types of data:
DL7-apo-sys
DL12: BIOPAX converters for GINsim and
ConsensusPathDB:
DL12-apo-sys
DL18: Development of a real-time measurement
system for the assessment of caspase8/-10 activation:
DL18-apo-sys
DL20: Systematic explaration and
validation of genes affecting mitochondrial-mediated cell death
triggered by cisplatin:
DL20-apo-sys
DL24: Top-level mathematical model of
cell fate decission:
DL24-apo-sys
DL33: Synergetic interaction between
IAP inhibitors and chemotherapy of TRAIL:
Dl33-apo-sys
DL39: Single Cell, real-time
measurements of pathways of apoptotic signaling:
DL39-apo-sys
DL54: Development of new algorithms
to process and model data:
DL54-apo-sys
DL68: In vivo analysis of AIF
death pathways in a define murine model:
DL68-aposys
DL75: Report on theoretical model studies in different
formalisms, including describing qualitative behaviors, robustness and
model checking:
DL75-aposys
News
EU-CORDIS-funded research sheds light on 'shock-and-kill' strategy against HIV-1 -read comment
Europa-Press release Rapid: Fight against cancer: contribution of EU-funded research - read comment
PS Public
Service Review: European Union:
http://www.publicservice.co.uk
nr.20, page 228-229
Weekendavisen
“Kræftcellernes svage punkt" (Kirkegaard et al.,
2010):
http://www.weekendavisen.dk/search/node/hsp70
"Deadline", Danmarks Radio (DR2) (Kirekegaard et
al., 2010:
http://www.dr.dk/dr2/deadline2230
Books
Systems biology analysis of cell death
pathways in cancer: how collaborative and interdisciplinary research
helps. In Cesario A and Marcus F B (editors)
(2011) Cancer Systems Biology: Bioinformatics and Medicine: Research
and Clinical Applications. Springer Dordrecht Heidelberg London New
York. pp. 267-296.
Understanding
different types of cell death using Systems Biology. In:
Lavrik I (Editor). Calzone, L., Zinovyev, A., and Zhivotovsky, B.
“Systems Biology of apoptosis”. Springer Science, NY, USA, 2012 (In
Press).
Different modes of cell death induced by
DNA damage. In: Greim H and Albertini R (Editors).
Surova, O., and Zhivotovsky, B. “The Cellular Response to the
Genotoxic Insult: The Question of Threshold for Genotoxic
Carcinogens”. RSC Publishing, 2012 (In Press).
